Effect of random and hub gene disruptions on environmental and mutational robustness in Escherichia coli

BMC Genomics

Table 2 Summary of significance tests for mean and variance effects of environmental and mutational robustness.

Source¹	Test statistic²	P
Environmental robustness:
Disruption type	3.5	0.064
Disruption type × environment	32.1	<0.001
Strain(disruption type) variance	9.6	0.001
Mutational robustness:
Disruption type	39.4	<0.001
Strain(disruption type) variance	0.7	0.201

¹ Disruption type was treated as a fixed effect. Environment and strain were treated as random effects.
² Significance of the fixed effect, disruption type, was tested with a partial F-test. Random effects were tested with likelihood ratio tests.

ISSN: 1471-2164