Skip to main content


Table 5 PPIase repertoire of Cryptococcus neoformans.

From: Identification and comparative analysis of sixteen fungal peptidyl-prolyl cis/trans isomerase repertoires

  PPIase Uniprot Acc. # kDa Signal Seq. Predicted Localisation Domain Architecture
Cyclophilins Cyp1 Q5KHA8* 18.2 ~ Cytoplasmic  
  Cyp2 Q5KKX7 18.7 ~ Cytoplasmic PPIase only
  Cyp3 Q5KMM0 19.5 ~ Cytoplasmic PPIase only
  Cyp4 Q5KA96 19.6 ~ Cytoplasmic PPIase only
  Cyp5 Q5KML4 21.1 ~ Mitochondrial PPIase only
  Cyp6 Q5KHA0 21.6 ~ Cytoplasmic PPIase only
  Cyp7 Q5KEB7 25.0 N-term. ER PPIase only
  Cyp8 Q5KFV5 40.9 ~ Cytoplasmic N-term. PPIase only
  Cyp9 Q5KNY5 57.9 ~ Nuclear N-term. PPIase, Central RRM
  Cyp10 Q5KA10 60.4 ~ Nuclear N-term. PPIase, C-term. Positively charged.
  Cyp11 Q5KAW8 63.6 ~ Cytoplasmic N-term. U-Box, C-term. PPIase
  Cyp12 Q5KMG4 72.9 ~ Cytoplasmic N-term. WD-40 (1x), C-term. PPIase
  Cwc27 Q5KAB3 55.2 ~ Nuclear N-term. PPIase, C-term. Positively charged
FKBPs FKBP1 Q5KMG3* 11.6 ~ Cytoplasmic FKBP (1x) only
  FKBP2 Q5KGT9 15.7 N-term. ER FKBP (1x) only
  FKBP3 Q5KIJ5 44.4 N-term. ER N-term. Negatively charged, C-term. FKBP (1x)
Parvulin Pin1 Q8NJN5 19.5 ~ Nuclear N-term. WW domain, C-term. Rotamase
  1. * manually re-annotated.