Effect of variation in expression ratios on their statistical significance. Scatter plots of FDR corrected nlPv (negated log transformed p-value) from the Limma analysis of the OneRA and the TwoRA DRG and SN samples. As a result of negating the p-values, large nlPv indicate stronger evidence of differential expression. Data points in red represent the FCE probesets. The dashed line is at nlPv = 10 in the TwoRA, above which genes may be considered significant.