Distribution of STAT1 binding sites within the ENCODE region. Levels of differential STAT1 binding in response to IFN-γ (ΔSTAT1; black line) are plotted for ENCODE regions containing one or more probes exhibiting differential binding over a cut-off of 0.4 (red line). Probe intensities were smoothed as described in Methods. Arrows indicate locations and directions of known genes, and are colored to improve visual discrimination. All raw data were obtained from Rozowsky et al.'s tiling array analysis of STAT1 binding in response to IFN-γ . Differential STAT1 binding values are on the log2 scale.