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Table 6 Pearson correlation analysis of selected gene expression changes measured by microarray and RTqPCR with DNA adduct levels

From: Time- and concentration-dependent changes in gene expression induced by benzo(a)pyrene in two human cell lines, MCF-7 and HepG2

Gene Cell line Microarray and RTq-PCR Microarray and DNA adducts RTq-PCR and DNA adducts
   Pearson Correlation Coefficient
AKR1C3 MCF-7 0.723 0.298 0.452
  HepG2 0.765 0.138 -0.481
BAX MCF-7 0.828 0.783 0.976
  HepG2 0.704 0.302 0.144
CDKN1A MCF-7 0.947 0.953 0.968
  HepG2 0.634 0.694 0.791
HISTH13D MCF-7 0.967 -0.905 -0.983
  HepG2 0.762 -0.240 0.082
IER3 MCF-7 -0.225 0.243 -0.921
  HepG2 0.879 0.764 0.633
PCNA MCF-7 0.882 -0.520 -0.272
  HepG2 0.784 0.092 -0.048
NQO1 MCF-7 0.879 0.923 0.980
  HepG2 0.419 -0.433 0.617
CYP1B1 MCF-7 0.125 -0.045 -0.204
  HepG2 -0.308 -0.537 0.251
  1. 1Values in bold are significant Pearson correlation coefficients (p < 0.05).