Table 6 Pearson correlation analysis of selected gene expression changes measured by microarray and RTqPCR with DNA adduct levels
Gene | Cell line | Microarray and RTq-PCR | Microarray and DNA adducts | RTq-PCR and DNA adducts |
|---|---|---|---|---|
| Â | Â | Pearson Correlation Coefficient | ||
AKR1C3 | MCF-7 | 0.723 | 0.298 | 0.452 |
| Â | HepG2 | 0.765 | 0.138 | -0.481 |
BAX | MCF-7 | 0.828 | 0.783 | 0.976 |
| Â | HepG2 | 0.704 | 0.302 | 0.144 |
CDKN1A | MCF-7 | 0.947 | 0.953 | 0.968 |
| Â | HepG2 | 0.634 | 0.694 | 0.791 |
HISTH13D | MCF-7 | 0.967 | -0.905 | -0.983 |
| Â | HepG2 | 0.762 | -0.240 | 0.082 |
IER3 | MCF-7 | -0.225 | 0.243 | -0.921 |
| Â | HepG2 | 0.879 | 0.764 | 0.633 |
PCNA | MCF-7 | 0.882 | -0.520 | -0.272 |
| Â | HepG2 | 0.784 | 0.092 | -0.048 |
NQO1 | MCF-7 | 0.879 | 0.923 | 0.980 |
| Â | HepG2 | 0.419 | -0.433 | 0.617 |
CYP1B1 | MCF-7 | 0.125 | -0.045 | -0.204 |
| Â | HepG2 | -0.308 | -0.537 | 0.251 |