From: Gene expressions and copy numbers associated with metastatic phenotypes of uterine cervical cancer
Univariate analysis | Multivariate analysis | |||||
---|---|---|---|---|---|---|
Covariate1 | p | Relative risk | 95% CI | p | Relative risk | 95% CI |
Model containing clinical variables alone | ||||||
Tumor volume | < 0.0001 | 1.01 | 1.01 – 1.02 | < 0.0001 | 1.01 | 1.01 – 1.02 |
Number of pathological lymph nodes | 0.015 | 1.3 | 1.1 – 1.7 | 0.24 | ||
Metastatic status | 0.30 | 1.7 | 0.64 – 4.3 | 0.47 | ||
Model containing gene variables alone | ||||||
Gene expressions | ||||||
MRPL11 | 0.0001 | 5.6 | 2.3 – 14 | 0.001 | 4.9 | 1.9 – 13 |
PDK2 | 0.013 | 3.2 | 1.3 – 7.9 | 0.008 | 3.8 | 1.4 – 10 |
CKS2 | 0.026 | 2.7 | 1.1 – 6.6 | 0.30 | ||
TBX3 | 0.028 | 0.37 | 0.15 – 0.90 | 0.006 | 0.24 | 0.09 – 0.67 |
MRPS23 | 0.032 | 2.7 | 1.1 – 6.9 | 0.87 | ||
MSN | 0.035 | 0.31 | 0.10 – 0.92 | 0.40 | ||
KLF3 | 0.035 | 0.37 | 0.15 – 0.93 | 0.47 | ||
LSM32 | 0.058 | 2.7 | 0.97 – 7.4 | 0.30 | ||
Model containing clinical and gene variables | ||||||
Tumor volume | < 0.0001 | 1.01 | 1.01 – 1.02 | |||
PDK2 | 0.013 | 3.3 | 1.3 – 8.3 | |||
MRPL11 | 0.26 | |||||
TBX3 | 0.12 |