Genome-wide sequence and functional analysis of early replicating DNA in normal human fibroblasts

BMC Genomics

Table 1 Distribution of islands.

Chromosome	Percent Enrichment¹	Mean Replication Timing Ratio²
19	198%	1.72
17	183%	1.64
16	175%	1.56
22	160%	1.75
15	123%	1.57
10	120%	1.49
11	113%	1.49
1	112%	1.52
7	110%	1.45
20	101%	1.60
12	97%	1.50
9	96%	1.44
8	89%	1.39
6	82%	1.44
14	82%	1.46
18	79%	1.42
2	79%	1.43
5	73%	1.42
3	71%	1.43
21	66%	1.42
4	55%	1.34
13	48%	1.36
X	28%	1.38
Y	25%	1.32

1- The percentage of total DNA in islands that originated from each chromosome was determined and compared to the percentage of genomic DNA for each chromosome.
2- Mean replication timing ratio for each chromosome as reported in Woodfine et al. [19]. Higher numbers indicate an earlier average time of replication.

ISSN: 1471-2164