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Table 5 Effect of time since initial creation of linkage disequilibrium (LD).

From: Linkage disequilibrium interval mapping of quantitative trait loci

t

MSE

Difference in MSE P value

 

T2

HAPim

 

50

0.69

0.64

0.495

100

0.52

0.44

0.135

200

0.41

0.26

< 0.001**

300

0.25

0.17

0.005**

  1. *: P < 0.05, ** : P < 0.01
  2. Mean square errors (MSEs) in cM2 of quantitative trait locus (QTL) location estimates obtained by the T2 and HAPim methods for various values of time t since initial LD creation. The single nucleotide polymorphism (SNP) marker spacing was 0.125 cM, N = 400, and the initial association was complete.
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BMC Genomics

ISSN: 1471-2164

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