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Table 5 Effect of time since initial creation of linkage disequilibrium (LD).

From: Linkage disequilibrium interval mapping of quantitative trait loci

t MSE Difference in MSE P value
  T2 HAPim  
50 0.69 0.64 0.495
100 0.52 0.44 0.135
200 0.41 0.26 < 0.001**
300 0.25 0.17 0.005**
  1. *: P < 0.05, ** : P < 0.01
  2. Mean square errors (MSEs) in cM2 of quantitative trait locus (QTL) location estimates obtained by the T2 and HAPim methods for various values of time t since initial LD creation. The single nucleotide polymorphism (SNP) marker spacing was 0.125 cM, N = 400, and the initial association was complete.