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Table 1 Relation between RSCU' and measures of expression for all codons of amino acids of degeneracy greater than one. For each codon, only the genes in which the corresponding amino acid has a frequency of at least 10 were considered. Major codons are underlined. w indicates G/U wobble (by Lander et al. 2001). * indicates translationally weak codons. The (+) sign indicates that the average RSCU' in class of 25% lowly expressed genes is significantly lower than the average RSCU' in class of 25% highly expressed genes, while the (-) sign represents the opposite. N.S. indicates that the RSCU' is not significantly different

From: The action of selection on codon bias in the human genome is related to frequency, complexity, and chronology of amino acids

A B C D E
Amino acid Codon tRNA GCN RSCU vs maximum expression RSCU vs breadth of expression
Ala GCA 9 N.S. +
  GCCW 0 N.S. -
  GCG* 5 - -
  GCT 29 + +
Arg2 AGA 6 N.S. +
  AGG 5 - -
Arg4 CGA 6 N.S. +
  CGCW 0 N.S. -
  CGG 5 N.S. N.S.
  CGT 7 N.S. N.S.
Asn AAC 28 N.S. -
  AATW 1 N.S. N.S.
Asp GAC 18 - -
  GATW 0 + +
Cys TGC 30 N.S. N.S.
  TGTW 0 N.S. N.S.
Gln CAA* 11 - -
  CAG 21 + +
Glu GAA 12 N.S. +
  GAG 13 N.S. -
Gly GGA 9 N.S. +
  GGC 15 + N.S.
  GGG* 7 - -
  GGTW 0 + +
His CAC 11 N.S. N.S.
  CATW 0 N.S. N.S.
Ile ATA* 5 - -
  ATCW 5 + N.S.
  ATT 14 N.S. +
Leu2 TTA 7 - N.S.
  TTG 6 N.S. N.S.
Leu4 CTA* 3 - N.S.
  CTCW 0 - -
  CTG 10 + N.S.
  CTT 12 - N.S.
Lys AAA 17 - N.S.
  AAG 17 N.S. N.S.
Phe TTC 12 N.S. N.S.
  TTTW 0 N.S. +
Pro CCA 7 + +
  CCCW 0 - -
  CCG* 4 - -
  CCT 10 N.S. +
Ser2 AGC 8 N.S. N.S.
  AGTW 0 N.S. +
Ser4 TCA 5 N.S. +
  TCCW 0 - -
  TCG* 4 - -
  TCT 11 + +
Thr ACA 8 N.S. +
  ACCW 0 N.S. -
  ACG* 6 - -
  ACT 10 N.S. N.S.
Tyr TAC 14 N.S. -
  TATW 1 N.S. +
Val GTA* 5 N.S. +
  GTCW 0 N.S. N.S.
  GTG 16 - -
  GTT 11 N.S. +