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Table 2 Comparison of mutant and gene positions

From: Large-scale mapping of mutations affecting zebrafish development

Abbr.

Allele

LG

Pos.

Gene

Gene Pos.

Panels

Diff.

acc

tq206

3

52.3

atp2a1

54.00

T51, HS

-1.70

boz

th211

15

57.3

dharma

57.77

LN54, HS

-0.47

cdy

te216

11

0.5

slc11a2

0.00

HS

0.50

con

tf18b

20

96.2

disp1

98.57

HS

-2.37

dtr

tm276b

6

85.3

gli1

85.40

MGH, HS

-0.10

eya1

tm90b

24

36.2

eya1

42.90

LN54, T51

-6.70

frs

tg280a

8

82.2

slc25a37

[LG17]

HS a

n.d.

ika

tm127c

14

33.0

fgf24

34.97

T51

-1.97

kgg

tl240a

14

57.2

cdx4

56.00

T51, HS, MOP

1.20

mfn

tc263

1

37.2

tll1

37.10

MGH, HS

0.10

mib

ta52b

2

20.9

mib

35.54

T51

-14.64

mon

tg234

8

42.5

trim33

52.85

HS, T51

-10.35

mot

tm303c

16

41.6

epb41

46.90

T51

-5.30

nic

dtbn12

6

31.1

chrna1

43.62

HS, T51, MOP, LN54

-12.52

oep

tz257

10

20.0

oep

12.20

LN54, T51

7.80

ovl

tz288

9

50.1

ift88

[LG13]

HS b

n.d.

ris

tb237

17

47.9

sptb

45.50

HS, MGH

2.40

spt

tm41

8

94.2

tbx16

96.03

T51, LN54, MOP

-1.83

suc

tf216b

19

20.9

edn1

11.90

MGH, LN54, T51

9.00

ubo

tp39

16

24.2

prdm1

28.08

LN54

-3.88

you

ty97

7

40.5

scube2

37.90

HS

2.60

  1. Map positions of mutations that were mapped in our project and cloned by other researchers are shown together with the ZMAP positions of the affected genes (publicly available from ZFIN [10]). The gene positions originate from several mapping panels: MGH [5] [6] [7]; Heat Shock (HS) [14] [15] [16], T51 [26] [27] [28] (Yi Zhou and Leonard Zon, unpublished data); LN54 [29] [30]; and Mother of Pearl (MOP) [31]. References to the original publications of the individual genes are not included here due to space constraints, but are likewise available from ZFIN. The map positions were subsequently intercalated into the MGH genetic map to produce the integrated ZMAP (Allen Day, Tom Conlin and John H. Postlethwait, unpublished). If a gene was mapped on more than one panel, the median position is shown. Only genes or gene-encoded markers directly placed on ZMAP are shown (rather than genes mapped through genomic clones or linked markers). Such data are available for 21 genes out of the 42 that are known to correspond to mutations in Additional file 1. Allele: allele designation; Abbr.: mutant abbreviation; LG: linkage group; Pos.: map position (cM distance from the top of the LG); Gene: gene symbol; Gene Pos.: Median gene position on ZMAP (cM distance from the top of the LG); Panels: mapping panels on which the gene was mapped; Diff.: difference between mutant and gene positions (cM). a Assignment to LG8 supported by published marker linkages [17]. b Assignment to LG9 supported by the T51 panel (as shown on the ZFIN website) and by the latest version of the HS map [18].