Table 3 Topological and functional association of prostate CGPs
From: Evidence for systems-level molecular mechanisms of tumorigenesis
Non-redundant significant terms* | GO level | P value FDR-adjusted |
|---|---|---|
Data set 1 | ||
Cluster A | ||
BP: Protein amino acid phosphorylation | 8 | 9.12E-03 |
CC: Plasma membrane | 4 | 2.25E-02 |
MF: Protein-tyrosine kinase activity | 7 | 9.12E-03 |
Cluster B | ||
BP: Cell-matrix adhesion | 5 | 4.29E-02 |
CC: Extracellular space | 3 | 4.09E-04 |
MF: Metalloendopeptidase inhibitor activity | 6 | 3.75E-03 |
Cluster C | ||
BP: Intracellular signaling cascade | 5 | 3.74E-02 |
CC: Cytoskeleton | 4 | 4.11E-02 |
MF: Protein-tyrosine kinase activity | 7 | 1.76E-03 |
KEGG: T cell receptor signaling pathway | 1.18E-02 | |
Adherens junction | 2.21E-02 | |
Focal adhesion | 4.11E-02 | |
Cluster D | ||
BP: Macromolecule biosyntesis | 5 | 3.17E-02 |
CC: Cytosolic ribosome | 5 | 2.30E-02 |
MF: Structural constituent of ribosome | 7 | 6.86E-03 |
KEGG: Ribosome | 6.86E-03 | |
Data set 2 | ||
Cluster E | ||
MF: Purine nucleotide binding | 4 | 1.51E-03 |
Cluster F | ||
CC: Extracellular space | 3 | 8.00E-03 |
MF: Extracellular matrix structural constituent | 3 | 8.00E-03 |
KEGG: Extracellular matrix receptor interaction | 8.00E-03 | |
Cluster G | ||
BP: Regulation of programmed cell death | 5 | 4.32E-02 |
MF: Protein kinase activity | 6 | 2.18E-02 |
KEGG: Insulin signaling pathway | 4.62E-02 | |
Cluster H | ||
BP: Phosphate transport | 8 | 1.27E-02 |
CC: Extracellular space | 3 | 1.10E-12 |
MF: Metalloendopeptidase inhibitor activity | 6 | 3.05E-02 |
KEGG: Extracellular matrix receptor interaction | 2.07E-03 |