Figure 4

The top ten TRANSFAC motifs with the lowest classification error in the promoters of the hepatocyte-specific genes. The motifs in the promoters (-1000 bp-200 bp around the transcription start sites) of hepatocyte-specific genes (S _value more than 2) were compared with those of non-hepatocyte-specific (S _value less than -2) using Motifclass software. For each motif the TRANSFAC matrix ID, corresponding binding factors, and the classification error ratio (broken down into sensitivity and specificity) are shown in columns. Sequence logo builds from the PWM for the motif matrix enriched in hepatocyte-specific genes are shown on the right.