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Table 4 Overrepresented Gene Ontologies among 604 probes showing differential expression in sex-independent comparison between WL and RJ.

From: Differential gene expression in femoral bone from red junglefowl and domestic chicken, differing for bone phenotypic traits

Type 1 GO-ID 2 GO-Name List Hits 3 Total Hits 4 EASE-score 5
C GO:0005842 cytosolic large ribosomal subunit (sensu Eukaryota) 12 45 6.21 E-09
P GO:0006412 protein biosynthesis 16 143 1.88 E-07
C GO:0005843 cytosolic small ribosomal subunit (sensu Eukaryota) 8 32 3.53 E-06
C GO:0005840 ribosome 9 45 6.91 E-06
P GO:0007165 signal transduction 24 428 6.08 E-05
F GO:0003735 structural constituent of ribosome 11 97 1.79 E-04
P GO:0000004 biological_process unknown 72 2067 2.28 E-04
F GO:0003723 RNA binding 20 268 2.41 E-04
P GO:0006461 protein complex assembly 7 62 4.98 E-04
C GO:0005856 cytoskeleton 11 108 5.03 E-04
P GO:0006508 proteolysis and peptidolysis 10 131 8.84 E-04
C GO:0005813 centrosome 6 39 1.05 E-03
C GO:0005794 Golgi apparatus 9 94 2.45 E-03
P GO:0006955 immune response 7 81 2.50 E-03
P GO:0007268 synaptic transmission 9 128 2.78 E-03
P GO:0006629 lipid metabolism 6 64 3.29 E-03
F GO:0005554 molecular_function unknown 62 1461 5.76 E-03
F GO:0016301 kinase activity 6 57 7.39 E-03
F GO:0008248 pre-mRNA splicing factor activity 6 58 8.06 E-03
C GO:0005622 intracellular 12 178 9.61 E-03
C GO:0008372 cellular_component unknown 71 1763 0.013
P GO:0006468 protein amino acid phosphorylation 9 171 0.017
P GO:0008283 cell proliferation 7 134 0.035
C GO:0005634 nucleus 62 1587 0.035
F GO:0003924 GTPase activity 6 81 0.037
C GO:0016021 integral to membrane 47 1179 0.047
  1. 1 Top-level Gene Ontology: P = biological process, C = cellular component, F = molecular function
  2. 2 Gene Ontology IDs of enriched terms
  3. 3 List Hits to Category: Numbers of DE probes on microarray belonging to specific GO-IDs. Total numbers of occurrences of C, P and F among 604 DE probes were: C = 408, P = 403 and F = 415.
  4. 4 Total Hits to Category: Total numbers of probes on microarray belonging to specific GO-ID. Total numbers of occurrences of C, P and F among all probes on microarray were: C = 13074, P = 17435 and F = 13433.
  5. 5 EASE-Score: Indicates the statistical significance of the observed overrepresentation.