Table 2 Optimum model details and test results. Expression levels in ES and differentiating (Diff) cells are used to make the signature pattern for the model. A 1 indicates that a gene is used in a model, 0 that it is not.
| Â | Â | Expression in | Models | Â | ||||
|---|---|---|---|---|---|---|---|---|
Gene Symbol | Entrez ID | ES | Diff | 1 | 2 | 3 | all | Gene Name |
Stmn2 | 20257 | 405.51 | 159.89 | 1 | 1 | 1 | 1 | stathmin-like 2 |
Tcea3 | 21401 | 175.47 | 67.29 | 1 | 1 | 1 | 1 | transcription elongation factor A (SII), 3 |
Igsf4a | 54725 | 63.81 | 158.42 | 1 | 1 | 0 | 1 | immunoglobulin superfamily, member 4A |
Pitx2 | 18741 | 87.00 | 348.96 | 1 | 1 | 1 | 1 | paired-like homeodomain transcription factor 2 |
Ramp2 | 54409 | 93.57 | 247.39 | 1 | 0 | 1 | 1 | receptor (calcitonin) activity modifying protein 2 |
Tead2 | 21677 | 218.96 | 617.77 | 0 | 1 | 1 | 1 | TEA domain family member 2 |
| Â | Model Sensitivity (%) | Model Specificity (%) | ||||||
Data Set | 1 | 2 | 3 | All | 1 | 2 | 3 | All |
Affymetrix data sets (n = 47) | 95.0 | 95.0 | 95.0 | 95.0 | 100.0 | 100.0 | 100.0 | 100.0 |
MPSS tpm count (n = 4) | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 |
NIA/Whitehead-Jaenisch cDNA arrays (n = 16) | 100.0 | 100.0 | 100.0 | 100.0 | NA | NA | NA | NA |
Whole data set | 97.4 | 97.4 | 97.4 | 97.4 | 100.0 | 100.0 | 100.0 | 100.0 |