Table 2 Positively affected transcription factors in the long-lived mutants. The "num" column indicates the number of target genes of a transcription factor under a specific condition at the 0.01 significance level according to the ChIP-chip data.
From: Inference of transcription modification in long-live yeast strains from their expression profiles
Transcription Factor | Condition | Num | sch9Δ/wt | rasΔ/wt | tor1Δ/wt | |||
|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | p-value | q-value | p-value | q-value | p-value | q-value |
CIN5 | H2O2Hi | 177 | 0.0022 | 0.012 | 7.5E-06 | 1.1E-04 | 0.0025 | 0.013 |
CIN5 | H2O2Lo | 315 | 4.5E-05 | 4.7E-04 | 2.4E-07 | 5.1E-06 | 0.0021 | 0.011 |
CIN5 | YPD | 274 | 0.0036 | 0.037 | 8.6E-07 | 3.5E-05 | 5.1E-04 | 0.0071 |
FHL1 | H2O2Hi | 188 | 0 | 0 | 8.8E-09 | 2.3E-07 | 2.2E-16 | 1.2E-14 |
FHL1 | RAPA | 214 | 0 | 0 | 5.6E-16 | 2.8E-14 | 0 | 0 |
FHL1 | SM | 287 | 0 | 0 | 1.5E-12 | 5.5E-11 | 0 | 0 |
FHL1 | YPD | 207 | 0 | 0 | 1.8E-14 | 1.7E-12 | 0 | 0 |
FKH2 | H2O2Hi | 331 | 0.0015 | 0.0087 | 1.3E-05 | 1.6E-04 | 1.4E-05 | 1.7E-04 |
GAT3 | YPD | 176 | 1.8E-14 | 1.7E-12 | 2.7E-08 | 1.4E-06 | 0 | 0 |
MET31 | YPD | 69 | 0.041 | 0.24 | 1.1E-04 | 0.0021 | 1.8E-04 | 0.0030 |
MET32 | SM | 93 | 1.4E-04 | 0.0012 | 1.8E-06 | 2.8E-05 | 1.4E-05 | 1.7E-04 |
MSN2 | Acid | 145 | 9.1E-04 | 0.0058 | 1.2E-05 | 1.6E-04 | 6.8E-07 | 1.2E-05 |
NDD1 | YPD | 190 | 0.037 | 0.23 | 2.8E-04 | 0.0041 | 8.2E-05 | 0.0017 |
NRG1 | H2O2Hi | 275 | 0.0087 | 0.035 | 5.5E-05 | 5.5E-04 | 0.088 | 0.22 |
NRG1 | H2O2Lo | 122 | 0.12 | 0.27 | 3.9E-06 | 5.8E-05 | 0.0081 | 0.033 |
PDR1 | YPD | 163 | 3.6E-06 | 1.3E-04 | 2.0E-04 | 0.0031 | 4.0E-06 | 1.3E-04 |
PUT3 | H2O2Lo | 156 | 4.7E-05 | 4.9E-04 | 2.4E-04 | 0.0019 | 0.0015 | 0.0086 |
RAP1 | SM | 387 | 0 | 0 | 5.7E-09 | 1.6E-07 | 1.1E-16 | 6.8E-15 |
RAP1 | YPD | 408 | 0 | 0 | 2.4E-10 | 1.6E-08 | 2.2E-16 | 3.2E-14 |
RGM1 | YPD | 107 | 2.3E-06 | 8.4E-05 | 3.1E-04 | 0.0045 | 4.0E-07 | 1.8E-05 |
RIM101 | H2O2Lo | 142 | 0.15 | 0.32 | 4.4E-04 | 0.0032 | 0.032 | 0.098 |
SFP1 | SM | 114 | 2.3E-15 | 9.9E-14 | 2.3E-07 | 5.1E-06 | 7.8E-16 | 3.6E-14 |
SMP1 | YPD | 181 | 1.2E-04 | 0.0022 | 0.0032 | 0.033 | 1.9E-04 | 0.0030 |
SOK2 | BUT14 | 211 | 0.043 | 0.12 | 8.4E-05 | 7.9E-04 | 0.0045 | 0.020 |
STB1 | YPD | 89 | 0.16 | 0.61 | 0.036 | 0.23 | 3.6E-05 | 9.3E-04 |
SWI4 | YPD | 252 | 0.0074 | 0.070 | 8.9E-05 | 0.0018 | 1.4E-06 | 5.5E-05 |
XBP1 | H2O2Lo | 173 | 0.027 | 0.087 | 3.5E-05 | 3.8E-04 | 0.023 | 0.076 |
YAP5 | YPD | 167 | 1.7E-10 | 1.2E-08 | 3.7E-06 | 1.3E-04 | 6.7E-12 | 5.8E-10 |
YAP6 | YPD | 167 | 0.0037 | 0.038 | 1.6E-09 | 9.9E-08 | 1.0E-05 | 3.0E-04 |