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Table 1 Genes differentially expressed by gender and the relevant functional groups.

From: Faster rates of post-puberty kidney deterioration in males is correlated with elevated oxidative stress in males vs females at early puberty

symbol

full name

biological processes

fold_change(male/female)

   

Mhm*BN

Mhm

US

Adam9

a disintegrin and metalloproteinase domain 9

metabolism

1.2

1.1

1.2

Bdh

3-hydroxybutyrate dehydrogenase

metabolism

1.1

1.1

1.2

Cdo1

cysteine dioxygenase 1

metabolism

1.5

1.5

1.9

Cyp2d22

cytochrome P450, family 2, subfamily d, polypeptide 22

metabolism

1.1

1.1

1.2

Dgat2

diacylglycerol O-acyltransferase homolog 2

metabolism

1.2

1.2

1.3

Gamt

guanidinoacetate methyltransferase

metabolism

1.3

1.6

1.9

Hnmt

histamine N-methyltransferase

metabolism

1.7

1.5

2.1

Idi1

isopentenyl-diphosphate delta isomerase 1

metabolism

1.3

1.2

1.4

Pecr

peroxisomal trans-2-enoyl-CoA reductase

metabolism

1.7

1.5

1.7

Pklr

pyruvate kinase, liver and red blood cell

metabolism

1.4

1.3

1.9

Sult1a1

sulfotransferase family 1A, phenol-preferring, member 1

metabolism

1.3

1.4

2.4

Sult1b1

sulfotransferase family 1B, member 1

metabolism

1.6

1.9

1.9

Prep

prolyl endopeptidase

metabolism; vascular biology

1.7

1.4

2

Gc

group specific component

metabolism; transport

1.5

1.2

1.9

Pzp

pregnancy-zone protein

metabolism; signal transduction

2

1.8

1.9

Dpp4

dipeptidylpeptidase 4

metabolism; signal transduction

1.3

1.2

1.3

Cacng5

calcium channel, voltage-dependent, gamma subunit 5

transport

1.4

1.4

2.2

Prom1

prominin 1

transport

1.6

1.6

1.8

Slc21a1

solute carrier organic anion transporter family, member 1a1

transport

2.5

2.9

3.7

Slc22a2

solute carrier family 22 (organic cation transporter), member 2

transport

2.8

3.2

4.3

Myo5a

myosin VA

transport

1.2

1.2

1.1

Rgn

regucalcin

transport; signal transduction

5.1

5.6

8

Basp1

brain abundant, membrane attached signal protein 1

proliferation

1.4

1.5

2.1

Tff3

trefoil factor 3

proliferation

2.5

2.3

4.7

Sod3

superoxide dismutase 3, extracellular

oxidative stress

0.5

0.4

0.4

Acadm

acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain

oxidative stress; metabolism

1.5

1.5

1.7

Snca

synuclein, alpha

oxidative stress; signal transduction

1.6

1.3

1.5

Afm

afamin

oxidative stress; transport

1.4

1.8

2

Slc19a1

solute carrier family 19, member 1

oxidative stress; transport

1.2

1.6

1.6

Agt

angiotensinogen (serpin peptidase inhibitor, clade A, member 8)

vascular biology

1.3

1.4

1.4

F2

coagulation factor II

vascular biology

1.8

1.4

2.2

Proc

protein C

vascular biology

1.4

1.2

1.5

Gucy1b2

guanylate cyclase 1, soluble, beta2

vascular biology; signal transduction

1.3

1.2

1.5

Adra1b

adrenergic receptor, alpha 1b

vascular biology; signal transduction

0.9

0.9

0.9

Sipa1l1

signal-induced proliferation-associated 1 like 1

signal tranduction

1.1

1.1

1.1

Cldn1

claudin 1

signal transduction

0.8

0.8

0.8

Asgr2

asialoglycoprotein receptor 2

signal transduction

1.2

1.1

1.2

Asrgl1

asparaginase like 1

signal transduction

1.2

1.3

1.5

Prlr

prolactin receptor

signal transduction

1.6

2

1.7