Figure 3
From: The functional modulation of epigenetic regulators by alternative splicing
Impact of alternative splicing in interaction domains. In all cases the part of the protein affected by alternative splicing is shown in yellow, while the remaining of the protein is shown in blue. (A) Chromodomain of human histone methyltransferase SUV39H2. One of the main strands of the β-sheet is missing in one of the alternative splice isoforms. (B) Bromodomain of human chromatin remodelling SMARCA2. One of the four helices of the helix bundle is lost in the alternative splice isoforms. The figures were obtained using the MOLSCRIPT software [65].