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Table 2 Estimated IC50 doses of breast cell lines treated with chemotherapeutics

From: EGFR associated expression profiles vary with breast tumor subtype

Cell Line

5-Florouracil (uM)

Doxorubicin (nM)

Carboplatin (uM)

Paclitaxel (nM)

ME16C

6.0 (0.29)

32.8 (1.89)

37.5 (0.63)

0.052 (0.004)

HME-CC

1.1 (0.07)

35.5 (3.26)

48.3 (1.41)

0.025 (0.003)

SUM102

16.8 (0.82)

5.1 (0.27)

11.7 (0.26)

0.00057 (0.00001)

SUM149

28.6 (1.33)

45.0 (3.06)

7.7 (0.24)

0.71 (0.006)

MCF-7

1.2 (0.15)

56.9 (4.26)

89.4 (3.79)

0.23 (0.02)

ZR-75-1

8.4 (1.06)

26.5 (1.39)

62.6 (1.98)

0.99 (3.34)

  1. Note that the standard errors are presented within ().