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Table 4 Comparison of expression ratios in patients with SALS and Alzheimer's disease

From: Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis

   Expression Ratios  
Gene Symbol UniGene ID SALS AD Comparison
AQP1 Hs.76152 2.52 1.62 =
CEBPD Hs.440829 2.52 1.77 ==
SERPINA3 Hs.534293 2.38 2.40 ==
SLC14A1 Hs.101307 2.15 2.20 ==
SLC12A5 Hs.21413 0.50 0.40 ==
CYCS Hs.437060 0.49 0.52 ==
DSCR1L1 Hs.440168 0.49 0.39 ==
NRGN Hs.524116 0.49 0.41 ==
PCP4 Hs.80296 0.49 0.32 =
ATP5A1 Hs.298280 0.48 0.61 ==
CAP2 Hs.132902 0.48 0.52 ==
GNAS Hs.125898 0.48 0.48 ==
NDUFA4 Hs.50098 0.48 0.62 ==
UCHL1 Hs.518731 0.48 0.67 ==
YWHAH Hs.226755 0.48 0.53 ==
PNMA2 Hs.521466 0.46 0.56 ==
RTN1 Hs.368626 0.46 0.37 ==
OLFM1 Hs.522484 0.43 0.55 ==
RTN4 Hs.429581 0.43 0.75 =
CHN1 Hs.380138 0.42 0.50 ==
MDH1 Hs.526521 0.41 0.54 ==
BEX1 Hs.334370 0.40 0.63 =
NEF3 Hs.458657 0.38 0.28 ==
VSNL1 Hs.444212 0.35 0.26 ==
ENC1 Hs.104925 0.34 0.74 =
NEFL Hs.521461 0.32 0.35 ==
SNAP25 Hs.167317 0.31 0.59 =
MT2A Hs.418241 2.43 1.31 <>
MT1E Hs.534330 2.29 1.32 <>
MT1G Hs.433391 2.19 1.36 <>
ANXA2 Hs.511605 2.06 1.45 <>
MT1X Hs.374950 2.02 1.39 <>
ATP1A3 Hs.515427 0.49 1.46 <>
ATP6V1A Hs.477155 0.49 0.78 <>
EGR1 Hs.326035 0.46 1.63 <>
EIF4A2 Hs.478553 0.45 0.75 <>
NSF Hs.431279 0.45 1.01 <>
CHGB Hs.516874 0.39 2.37 <>
  1. Expression ratios for candidate genes identified in the present report (SALS) are compared to those found for data by Blalock et al. [18] for Alzheimer's disease (AD), giving a correlation coefficient of r = 0.696. AD data were retrieved from GEO (series GSE1297) and processed as described in the Methods section.
  2. == both tissues give the same result, differing ≤1.5-fold
  3. = both tissues give the same result, differing >1.5-fold
  4. <> both tissues give different results (up- vs. down-regulation or deregulation vs. constancy, defining constancy as a ≤1.5-fold deregulation)
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