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Table 1 Differences between MG1655 and W3110 Kohara (CGSC # 7167)

From: An evaluation of Comparative Genome Sequencing (CGS) by comparing two previously-sequenced bacterial genomes

Location1 Gene b number Mutation CGS Detection Reported as:2 Status3
Small sequence differences
555954 ybcJ b0528 c>t yes SNP new
556858 folD b0529 a>t yes SNP new
1092487 ycdT b1025 c>t yes SNP known
1335418 acnA b1276 a>g yes SNP known
1650355 intQ b1579 t>c yes SNP known
2030447 yedJ b1962 g>a yes SNP known
2865477 rpoS b2741 g>a yes ROI known
3484227 crp b3357 c>a yes ROI known
4210321 rrlE b4009 g>a undetected   known
4364615 dcuA b4138 2 nt insertion yes ROI known
IS element insertions
654214 dcuC b0621 IS5 insertion yes ROI known
1104604 csgC-ymdA b1043 – 1044 IS2 insertion undetected   known
1298687 ychE-oppA b1242 – 1243 IS2 insertion undetected   known
1463456 ydbA b1401 IS2 insertion yes ROI new
1976519 flhD-yecG b1892 – 1895 IS5 insertion undetected   known
2033459 yedS – hchA b1966 – 1967 IS5 insertion yes ROI – 1 probe new
2172870 gatA b2094 IS5 insertion yes ROI known
2315483 rcsC b2218 IS2 insertion yes ROI known
2404811 lrhA-yfbQ b2289 – 2290 IS1 insertion yes ROI – 1 probe known
2696426 yfhB b2560 IS30 insertion yes ROI new
3260500 tdcD b3115 IS5 insertion yes ROI – 1 probe known
3378961 degQ b3234 IS2 insertion yes ROI new
3550943 malP-malT b3417 – 3418 IS5 insertion yes ROI new
3681321 dctA b3528 IS30 insertion yes ROI new
3886653 tnaA-tnaC b3707 – 3708 IS5 insertion yes ROI – 1 probe known
3889134 tnaB b3709 IS5 insertion yes ROI known
3891777 yieE-yidZ b3711 – 3712 IS2 insertion yes ROI known
4229085 yjbC b4022 IS2 insertion yes ROI new
4304907 alsK b4084 IS5 insertion yes ROI known
Deletions/Inversions
1395267 – 1397616 ynaJ-fnr b1332 – 1334 deletion yes ROI new
~2556721 – 2563354 intZ-yffS b2442 – 2450 deletion yes ROI known
3424826 – 4207943   b3276 – 4008 Inversion undetected   known
  1. 1. Location is given based on the MG1655 genome (GenBank accession # U00096.2)
  2. 2. Detected differences were reported by Nimblegen as Single Nucleotide Polymorphisms (SNPs) or in non-called Regions Of Interest (ROIs). Most differences detected in ROIs were reported by multiple nearby probes, but were reported in only one probe in cases as noted.
  3. 3. This column indicates whether the sequence difference is present in the published genome sequence of W3110.