Table 2 Genes that are differentially expressed in mesenteric white adipose tissue of OE-treated rats
From: Short-term oleoyl-estrone treatment affects capacity to manage lipids in rat adipose tissue
Ratio | GeneBank | Functional Classification | |
|---|---|---|---|
Down-regulated genes | |||
Fatty acid synthase (FAS) | 0.11 | M76767 | Metabolism of cofactors, vitamins & related substances |
Acetyl-CoA carboxylase (ACC) | 0.19 | J03808 | Simple Lipid metabolism |
Prostaglandin d2 receptor | 0.30 | U92289 | Hormone Receptors |
Fatty acid transport protein (FATP1) | 0.31 | U89529 | Other membrane channels & Transporters |
Very long chain acyl-coa dehydrogenase (vlcad) | 0.32 | D30647 | Metabolism of Cofactors, Vitamins & Related Substances |
Lipoprotein lipase (LPL) | 0.33 | L03294 | Complex Lipid Metabolism |
Slow voltage-gated potassium channel protein | 0.33 | M22412 | Voltage-gated ion channels |
Low density lipoprotein receptor | 0.35 | X13722 | Other receptors |
Pyruvate dehydrogenase kinase kinase | 0.37 | L22294 | Intracellular kinase network members |
Adipocyte fatty acid-binding protein (FABP4) | 0.38 | U75581 | Other Trafficking & Targeting proteins |
Carnitine palmitoyltransferase 1b (CPT1b) | 0.39 | D43632 | Simple Lipid metabolism |
Hormone-sensitive lipase (HSL) | 0.40 | U40001 | Simple Lipid Metabolism |
Cytochrome P450 2c7 | 0.42 | M18335 | Complex Lipid Metabolism |
Glucose-6-P-dehydrogenase | 0.45 | X07467 | Complex Carbohydrate Metabolism |
Retinoid X receptor beta | 0.45 | M81766 | Nuclear receptors |
Brain fatty acid binding protein | 0.45 | U02096 | Other Trafficking & Targeting proteins |
Adenyl cyclase | 0.46 | M80633 | Adenylate/Guanylate Cyclases & Diesterases |
Proteasome 26s subunit 2 | 0.47 | D50694 | Proteosomal Proteins |
Up-regulated genes | |||
Insulin receptor-related receptor alpha subunit | 1.52 | M90661 | Intracellular Kinase network members |
Cytochrome p450 4f5 | 1.72 | U39207 | Complex Lipid Metabolism |
Tumor necrosis factor alpha (TNFα) | 1.77 | X66539 | Growth Factors, Cytokines hemokines |
GTP-binding protein | 1.82 | L19699 | G Proteins |
Ras-gtpase activation protein | 1.85 | L13151 | GTP/GDP exchangers & GTPse activity modulators |
Cytochrome p450 4b1 | 2.01 | M29853 | Other Metabolism Enzymes |
Protein arginine n-methyltransferase 1 | 3.59 | U60882 | Intracellular Adaptors eceptor Associated Proteins |