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Table 3 Heteroplasmic sites identified by sequencing mtDNA CR (16531 nt_261 nt) in subjects showing DHPLC heteroplasmy levels equal to or higher than 25%.

From: The mitochondrial DNA control region shows genetically correlated levels of heteroplasmy in leukocytes of centenarians and their offspring

 

Mutations

 

G62A

T146C

C150T

T152C

G189A

Centenarians

1

1

4

 

1

Offspring of centenarians

 

1

4#

1

 

Controls

 

2*

1

 
  1. # One of the 4 children showing C150T heteroplasmy was the son of one of the 4 centenarians displaying C150T heteroplasmy.
  2. * Subjects showing heteroplasmy for both T146C and C150T mutations.
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BMC Genomics

ISSN: 1471-2164

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