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Table 1 Functional groups of genes represented on the Actichip microarray

From: Design and evaluation of Actichip, a thematic microarray for the study of the actin cytoskeleton

Gene function category Number of genes represented on Actichip Number of probes
Actin cytoskeleton Actins 7 8
  Actin nucleators 9 14
  Actin bundling (cross-linking, severing) 52 56
  Actin sequestrating 7 7
  Barbed end actin capping 6 6
  Pointed end capping 7 7
  Filamentous actin stabilisation 5 5
  Actin depolymerisation 11 11
  Actin-dependent motors 42 44
  Actin-related, actin-like proteins 16 16
  Actin-binding proteins 14 14
  Cytoskeletal proteins 21 21
  Plasma membrane cortical cytoskeleton linkers/scaffold, signalling 52 60
Actin-based processes Tissue-specific 4 5
  Cell adhesion 40 49
  Cancer 12 12
  Signalling 10 10
  DNA, transcription and translation factors 12 14
Total 327 359
  1. A set of 359 long oligonucleotides (60-mer) were designed to represent 249 genes encoding proteins implicated in the actin cytoskeleton machinery or 78 genes involved in actin-based processes. Most of the genes (301) are represented by a unique probe, 22 genes by two probes, 3 genes by 3 probes and one gene by 5 probes.