Table 2 Functional modules for breast cancer (FDR ≤ 0.1)
From: GO-2D: identifying 2-dimensional cellular-localized functional modules in Gene Ontology
Dimension | Biological Process Name (# of genes d in BP) | Cellular Component Name (# of genes d in CC) | # of genes d in 2D module | Observed P Value |
|---|---|---|---|---|
1Db | nucleosome assembly (31) | Â | Â | 8.33E-04 |
| Â | learning and/or memory (7) | --- | --- | 1.58E-03 |
2Dc | nucleosome assembly (31) | nucleosome (21) | 20 | 6.19E-05 |
| Â | nucleosome assembly (31) | nucleus (1779) | 31 | 8.33E-04 |
| Â | learning and/or memory (7) | cell part (4794) | 5 | 4.78E-04 |
| Â | oxygen and reactive oxygen species metabolism (36) | extracellular region part (257) | 5 | 4.78E-04 |
| Â | lipid biosynthesis (108) | mitochondrion (376) | 10 | 4.99E-03 |
| Â | complement activation (14) | extracellular region (388) | 11 | 6.68E-03 |
| Â | transmembrane receptor protein tyrosine kinase signalling pathway (73) | cytoplasmic part (1297) | 11 | 6.68E-03 |
| Â | G-protein coupled receptor protein signalling pathway (172) | integral to plasma membrane (459) | 61 | 7.07E-03 |