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Table 6 Equine RNASEL single nucleotide polymorphisms

From: Characterization of the equine 2'-5' oligoadenylate synthetase 1 (OAS1) and ribonuclease L (RNASEL) innate immunity genes

Region AccessionEF070193 Alleles Residue Amino Acid Type Frequency Polymorphism
- 143 C - - 0.12 Transversion
   G    0.88  
5' UTR 1857 A - - 0.55 Transversion
   C    0.45  
Exon 2 1991 C 27His Basic Polar 0.54 Transition
   T 27Tyr Uncharged Polar 0.46  
Exon 2 2020 C 36Gly Uncharged Polar 0.92 Transition
   T 36Gly   0.08  
Exon 2 2021 G 37Asp Acidic Polar 0.69 Transversion
   T 37Tyr Uncharged Polar 0.31  
Exon 2 2118 A 69Asn Uncharged Polar 0.29 Transversion
   C 69Thr Uncharged Polar 0.71  
Exon 2 2121 A 70Tyr Uncharged Polar 0.92 Transition
   G 70Cys Uncharged Polar 0.08  
Exon 2 2316 A 135Lys Basic Polar 0.75 Transversion
   C 135Thr Uncharged Polar 0.25  
Exon 2 2332 A 140Ala Nonpolar 0.35 Transition
   G 140Ala   0.65  
Exon 2 2374 G 154Arg Basic Polar 0.83 Transversion
   T 154Ser Uncharged Polar 0.17  
Exon 2 2635 A 241Thr Uncharged Polar 0.21 Transition
   G 241Thr   0.79  
Exon 2 2680 C 256Ser Uncharged Polar 0.43 Transversion
   G 256Ser   0.57  
Exon 2 2771 A 287Lys Basic Polar 0.57 Transition
   G 287Glu Acidic Polar 0.43  
Exon 2 3144 A 411Asn Uncharged Polar 0.19 Transition
   G 411Ser Uncharged Polar 0.81  
Exon 2 3152 C 414Arg Basic Polar 0.81 Transition
   T 414Cys Uncharged Polar 0.19  
Exon 2 3281 A 457Lys Basic Polar 0.19 Transition
   G 457Glu Acidic Polar 0.81  
Exon 2 3301 A 463Lys Basic Polar 0.19 Transversion
   C 463Asn Uncharged Polar 0.81  
Exon 2 3311 C 467Pro Nonpolar 0.19 Transition
   T 467Ser Uncharged Polar 0.81  
Exon 2 3372 A 487Gln Uncharged Polar 0.58 Transition
   G 487Arg Basic Polar 0.42  
Intron 2 3404 A - - 0.19 Transition
   G    0.81  
Exon 3 5108 A 513Lys Basic Polar 0.11 Transition
   G 513Glu Acidic Polar 0.89  
Exon 3 5111 C 514Pro Nonpolar 0.82 Transition
   T 514Ser Uncharged Polar 0.18  
Exon 5 7314 A 598Asn Uncharged Polar 0.87 Transition
   G 598Asp Acidic Polar 0.13  
3' UTR 9994 C - - 0.15 Transversion
   G    0.85  
3' UTR 9999 A - - 0.88 Transversion
   T    0.12  
3' UTR 10247 C - - 0.31 Transition
   T    0.69  
3' UTR 10914 C - - 0.38 Transition
   T    0.62  
3' UTR 11105 C - - 0.88 Transition
   T    0.12  
3' UTR 11146 C - - 0.35 Transition
   T    0.65  
3' UTR 11184 C - - 0.35 Transition
   T    0.65  
3' UTR 11228 C - - 0.83 Transition
   T    0.17  
  1. SNPs identified from sequencing RNASEL exons from 13 equine individuals, CHORI BAC 159N12 and the reference transcript sequence. Positions are identified from the genomic consensus sequence submitted to GenBank [GenBank: EF070193].