A Marfan syndrome gene expression phenotype in cultured skin fibroblasts

BMC Genomics

Table 3 Data summary of genes selected for validation by qRT-PCR

SwissProt Accession	Gene name	PDAR	MFS NI	UC NI	Ratio MFS/UC	q value
VDR:P11473	vitamin D receptor	Hs00172113_m1	59	84	1.42^-1	3.94E-11
FBN1:P35555	fibrillin 1	Hs00171791_m1	124	233	1.89^-1	2.52E-10
INHBA:P08476	inhibin, beta A	Hs00170103_m1	72	117	1.61^-1	3.48E-10
ELN:P15502	elastin	Hs00355783_m1	35	117	3.34^-1	2.19E-08
COL1A2:P08123	collagen, type I, alpha 2	Hs00164099_m1	3663	6582	1.80^-1	4.48E-06
PCOLCE:Q15113	procollagen C-endopeptidase	Hs00170179_m1	134	168	1.26^-1	2.99E-04
PLOD2:O00469	lysine hydroxylase 2	Hs00168688_m1	92	75	1.22	3.00E-04
PDCD10Q9BUL8	programmed cell death 10	Hs00200578_m1	534	464	1.15	1.29E-03
PTGES:O14684	prostaglandin E synthase	Hs00610420_m1	185	108	1.72	1.36E-03
LMO7:Q8WWI1	LIM domain only 7	Hs00245600_m1	50	45	1.13	5.07E-03

We selected 10 genes for validation based on their performance on the array. Column headings are as in Table 2, except PDAR: Applied Biosystems predetermined assay reagent identifier.

ISSN: 1471-2164