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Table 5 Gene variability by qRT-PCR

From: A Marfan syndrome gene expression phenotype in cultured skin fibroblasts

 

Interquartile range

Full range

# Outliers

Gene

UC

MFS

MFS/UC

UC

MFS

MFS/UC

UC

MFS

COL1A2

2.9

1.9

0.7

19.2

66.1

3.4

0

6

ELN

2.4

24.3

10.4

1190.4

1687.3

1.4

4

0

FBN1

1.6

3.3

2.0

4.4

69.3

15.6

0

2

INHBA

2.2

3.7

1.7

124.5

2218.2

17.8

4

3

LMO7

4.7

2.0

0.4

25.9

141.1

5.4

0

7

PCOLCE

2.6

1.8

0.7

5.9

295.5

50.3

0

5

PDCD10

1.8

1.4

0.8

103.6

64.7

0.6

1

6

PLOD2

2.0

3.1

1.5

16.0

251.2

15.7

1

3

PTGES

2.8

3.7

1.3

31.7

225.0

7.1

1

1

VDR

3.9

11.3

2.9

230.3

233.0

1.0

1

0

min

1.6

1.4

0.4

4.4

64.7

0.6

0.0

0.0

median

2.5

3.2

1.4

28.8

229.0

6.3

1.0

3.0

mean

2.7

5.7

2.2

175.2

525.1

11.8

1.2

3.3

max

4.7

24.3

10.4

1190.4

2218.2

50.3

4.0

7.0

# > 1

  

6

  

8

  
  1. For the 10 genes validated by qRT-PCR, we summarize variability across 32 UC and 42 MFS samples. Interquartile Range: fold change between the 25th and 75th percentiles. Full Range: fold change between the most extreme pair of samples. #Outliers: number of outliers (triangles in Figure 2). If the data were normally distributed, approximately 1% of the points would so identified, i.e., on average 0.32 per gene for UC and 0.42 per gene for MFS samples.
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BMC Genomics

ISSN: 1471-2164

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