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Figure 7 | BMC Genomics

Figure 7

From: The extracellular Leucine-Rich Repeat superfamily; a comparative survey and analysis of evolutionary relationships and expression patterns

Figure 7

Alignment of proteins in Elron cluster. Predicted amino acid sequences from Lrtm1, Lrtm2, Lrrc38, Lrrc55, Lrrc52 and BC004853 from the mouse were aligned with CLUSTALW. Brackets indicate the extent of predicted motifs (consensus limits are shown); the notch under the bracket indicates the end of the conserved N-terminal portion of each LRR. Arrowheads denote exon-intron boundaries. The short cytoplasmic domain is poorly conserved, but does contain similarly positioned acidic residues (E/D) in all members. Lrtm1 and 2 end in consensus PDZ-binding domains (SSSA/SSVA), underlined. Abbreviations, amino acid colour-code and conservation symbols as in Figure 7.

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BMC Genomics

ISSN: 1471-2164

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