Figure 8

Expression of Elfn genes in developing mouse brain. Expression as defined by RNA in situ hybridisation is shown for Elfn1 (A-C) and Elfn2 (D-F) in coronal sections of mouse brain at three ages (embryonic day 15 (E15), A, D; postnatal day zero (P0), B, E; and postnatal day 9 (P9), C, F). Elfn1 is strongly expressed in globus pallidus and interneurons in cortex and hippocampus, while Elfn2 is expressed in striatum and in projection neurons in cortex and hippocampus. Arrowheads in A and B indicate presumed interneurons migrating towards cortex. Abbreviations: cp, cortical plate; Cx, cortex; DG(vz), ventricular zone of dentate gyrus; gcl, granule cell layer (of dentate gyrus); GP, globus pallidus; hab, habenula; hc, hippocampus; hi, hilus (of dentate gyrus); hy, hypothalamus; pcl; pyramidal cell layer (of hippocampus); SB, subiculum; sp, subplate; so, stratum oriens (of hippocampus), str, striatum. Scale bar: E15, 200 microns; P0 and P9, 500 microns.