Table 7 Differentially expressed genes of the proteolysis
Symbol | Gene name | ACC.# | p value | GO Term | Fold change |
|---|---|---|---|---|---|
Psmc6 | Proteasome (prosome, macropain) 26S subunit, ATPase, 6 | CB518083 | 4.3E-02 | protein catabolism – GO:0030163 | -2.3 |
PSME2 | Proteasome (prosome, macropain) activator subunit 2 | CB491442 | 1.5E-02 | protein catabolism – GO:0030163 | -5.7 |
Ubc | Ubiquitin C | CA048031 | 9.6E-04 | ubiquitin-dependent protein catabolism-GO:0006511 | -2.8 |
UCHL5 | Ubiquitin carboxyl-terminal hydrolase L5 | CA053740 | 1.2E-02 | ubiquitin-dependent protein catabolism-GO:0006511 | -7.1 |
UBE1C | Ubiquitin-activating enzyme E1C (UBA3 homolog, yeast) | CA051243 | 4.6E-02 | proteolysis – GO:0006508 | -2.3 |
Ubb | Polyubiquitin | CB500037 | 6.5E-04 | protein ubiquitination – GO:0016567 : | -4.4 |
FBXO38 | F-box protein 38 | CB509947 | 4.2E-04 | ubiquitin cycle – GO:0006512 | -7.0 |
RBX1 | Ring-box 1 | CA062272 | 8.6E-03 | protein ubiquitination – GO:0016567 | -3.8 |
TRIM39 | Tripartite motif-containing 39 | CB514566 | 2.6E-02 | protein ubiquitination – GO:0016567 | -2.0 |
PITRM1 | Pitrilysin metallopeptidase 1 | CA050901 | 7.5E-03 | metalloendopeptidase activity-GO:0004222 | -3.2 |
TIMP2 | TIMP metallopeptidase inhibitor 2 | CB492841 | 2.0E-02 | enzyme inhibitor activity – GO:0004857 | -4.0 |
ACY1 | Aminoacylase 1 | CA054045 | 2.1E-02 | amino acid metabolism – GO:0006520 | -2.1 |
ITIH5 | Inter-alpha (globulin) inhibitor H5 | CA039272 | 3.6E-02 | hyaluronan metabolism – GO:0030212 | -2.8 |
Itih3 | Inter-alpha trypsin inhibitor, heavy chain 3 | CA037372 | 1.8E-02 | hyaluronan metabolism – GO:0030212 | -2.8 |
NUPR1 | P8 protein (candidate of metastasis 1) | CA043387 | 1.0E-02 | induction of apoptosis – GO:0006917 | -2.9 |
SQSTM1 | Sequestosome 1 | CB492474 | 1.8E-04 | apoptosis – GO:0006915 | -5.9 |
CASP10 | Caspase 10, apoptosis-related cysteine peptidase | CB498395 | 7.4E-03 | induction of apoptosis – GO:0006917 | -3.0 |
PDCD6 | Programmed cell death 6 | CB514639 | 1.1E-03 | apoptosis – GO:0006915 | 3.1 |
Rilp | Rab interacting lysosomal protein | CB517236 | 2.2E-02 | transport – GO:0006810 | -2.6 |
Edem1 | ER degradation enhancer, mannosidase alpha-like 1 | CA063288 | 3.4E-02 | response to unfolded protein-GO:0006986 | 2.3 |