Multiple splice variants within the bovine silver homologue (SILV) gene affecting coat color in cattle indicate a function additional to fibril formation in melanophores

Table 4 Expression of bovine SILV splice variants by splice site specific RT-PCR in differentially pigmented skin and non-pigmented tissues

Tissues	Δ105–362	Δ498–1340	Δ660–1340	Δ816–1340	Δ1185–1340	Δ1655–1748
Non-pigmented, heterozygous dilute, eumelaneic	-	+	+	+	++	+
pigmented, heterozygous dilute, eumelaneic	++	++	+	++	++	++
pigmented, homozygous dilute, eumelaneic	+	++	+	++	++	++
Non-pigmented, heterozygous dilute, phaeomelaneic	-	+	+	+	++	+
Pigmented, heterozygous dilute, phaeomelaneic	+	++	+	++	++	++
Non-pigmented, homozygous non-dilute, eumelaneic	+	++	+	++	++	++
Pigmented, homozygous non-dilute, eumelaneic	++	++	+	++	++	++
liver	-	-	-	+	-	-
duodenum	-	-	-	+	-	-
pituitary gland	-	-	-	+	-	-
lung	-	+	+	+	-	-
heart	-	-	-	+	-	-
kidney	-	+	-	+	-	+
mammary gland	-	+	-	+	+	+

-: no expression detected, + expression detected, ++ enhanced expression detected

ISSN: 1471-2164