Figure 5
From: Sample matching by inferred agonal stress in gene expression analyses of the brain
Comparing pH-matching and ASR-matching with an example. a. ASR and pH values for samples used in a test case, where a group of pH-matched major depression samples (in blue) were compared to controls (in red), while a second group of ASR-matched major depression samples (in green) were compared to the same controls. b. In an analysis of enrichment of Gene Ontology and KEGG pathway terms for the top genes, the pH-matched comparison still revealed significant effects for gene families and pathways known to be affected by the pH effect, while the same effect was much attenuated in the ASR-matched comparison.