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Table 1 The human, rat and mouse GPCR family repertoires

From: The G protein-coupled receptor subset of the rat genome

 

Human

Rat

Mouse

GPCR Family

Full- length

Pseudo- genes

Pseudo- genes (%)

New full- length

New pseudo- genes

Full- length

Pseudo- genes

Partial

Pseudo- genes (%)

New full- length

New pseudo- genes

Full- length

Pseudo- genes

Partial

Pseudo- genes (%)

New1 full- length

New1 pseudo- genes

Adhesion

33

2

6%

0

2

26

1

4

3%

0

2

30

1

 

3%

0

0

Frizzled

11

0

0%

0

0

10

1

 

9%

0

0

11

0

 

0%

0

0

Glutamate

22

0

0%

0

0

22

0

 

0%

0

0

22

0

 

0%

0

0

-V2R subgroup

1

11

92%

1

11

108

87

2

45%

23

53

111

183

1

62%

21

63

Rhodopsin

284

27

9%

0

1

297

7

4

2%

5

0

320

23

 

7%

3

NA*

-OR subgroup

388

479

55%

0

12

1234

552

28

31%

1234

552

1081

325

1

23%

NA*

NA*

Secretin

15

0

0%

0

0

15

0

 

0%

0

0

15

0

 

0%

0

0

Taste2

25

10

29%

0

0

35

6

 

15%

0

0

35

5

 

13%

0

0

Vomeronasal1

5

53

91%

0

53

105

84

 

44%

12

76

145

164

 

53%

17

92

Other GPCRs"

15

1

6%

0

1

15

1

 

14%

1

0

13

1

 

7%

1

0

Total

799

583

 

1

133

1867

739

38

 

1276

759

1783

702

2

 

43

247

  1. The human, rat and mouse GPCR families; their numbers of full-length, pseudogene and partial members; as well as the number of new members identified in this study. GPCR gene sequences were defined as new if their sequence was not available in a public database annotated as a GPCR. *No figure could not be calculated.