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Table 1 Differential gene expression between the permethrin resistant Odumasy and the susceptible Kisumu strain

From: Transcription profiling of a recently colonised pyrethroid resistant Anopheles gambiae strain from Ghana

Gene

Function

Cytological position

Accession number

Females

Males

    

Fold

p-Value

Fold

p-Value

Genes over-expressed in resistant Odumasy strain

CYP6M2

Cytochrome P450 monooxygenase

3R

[GenBank: AY193729]

5.2

7.94 × 10-05

3.2

1.29 × 10-11

CYP6Z2

Cytochrome P450 monooxygenase

3R

[GenBank: AF487780]

4.2

8.62 × 10-07

8.0

2.27 × 10-11

SOD3B

Cu-Zn superoxide dismutase

3L

[GenBank: AY745234, TIGR: TC54196]

3.5

8.11 × 10-04

2.0

1.00 × 10-04

GSTS1-2

Glutathione S-transferase

3L

GenBank: AF513639]

2.5

2.91 × 10-04

-

n.s.

COEJHE5E

Esterase

2L

[TIGR: TC77639]

2.0

3.86 × 10-09

1.8

1.67 × 10-08

CYP6Z3

Cytochrome P450 monooxygenase

3R

[GenBank: AY193727]

-

n.s.

3.0

1.54 × 10-07

Genes over-expressed in the susceptible Kisumu strain

GSTE2

Glutathione S-transferase

3R

[GenBank: AF316636]

-

n.s.

2.7

4.61 × 10-04

CYP6P1

Cytochrome P450 monooxygenase

2R

[GenBank: AY028785]

2.3

1.06 × 10-06

1.6

7.32 × 10-11

CYP6AJ1

Cytochrome P450 monooxygenase

3L

[GenBank: AY745226]

2.0

8.76 × 10-06

-

n.s.

PX7

Peroxidase

3L

[GenBank: AY752901]

-

n.s.

7.5

6.45 × 10-06

  1. Only genes are listed which showed at least a two-fold difference in one or both sexes. p-values were corrected for multiple testing as described in the materials and methods section. n.s., p ≥ 0.001.