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Table 4 Effect of inhibition of NADH dehydrogenase on the cytotoxicity of palmitate and TG accumulation

From: Identification of genes that regulate multiple cellular processes/responses in the context of lipotoxicity to hepatoma cells

Concentration LDH release (DAY 1) LDH release (DAY 2) TG (Day 1) ug/mg protein TG (Day 2) ug/mg protein
None 4.5 +/- 0.3 35.7 +/- 3.4 69.4 +/- 16.1 173.8 +/- 16.7
250 nM 3.4 +/- 0.3 * 24.9 +/- 1.4 * 63.3 +/- 14.2 191.1 +/- 12.1
500 nM 2.7 +/- 0.2 * 14.8 +/- 3.2 * 74.3 +/- 12.0 197.8 +/- 11.3
1000 nM 3.4 +/- 0.2 * 20.0 +/- 4.6 * 104.6 +/- 7.8 * 204.9 +/- 8.5 *
  1. *, significantly different than the no inhibitor condition, p < 0.01.