Table 4 Effect of inhibition of NADH dehydrogenase on the cytotoxicity of palmitate and TG accumulation
Concentration | LDH release (DAY 1) | LDH release (DAY 2) | TG (Day 1) ug/mg protein | TG (Day 2) ug/mg protein |
|---|---|---|---|---|
None | 4.5 +/- 0.3 | 35.7 +/- 3.4 | 69.4 +/- 16.1 | 173.8 +/- 16.7 |
250 nM | 3.4 +/- 0.3 * | 24.9 +/- 1.4 * | 63.3 +/- 14.2 | 191.1 +/- 12.1 |
500 nM | 2.7 +/- 0.2 * | 14.8 +/- 3.2 * | 74.3 +/- 12.0 | 197.8 +/- 11.3 |
1000 nM | 3.4 +/- 0.2 * | 20.0 +/- 4.6 * | 104.6 +/- 7.8 * | 204.9 +/- 8.5 * |