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Figure 3 | BMC Genomics

Figure 3

From: The functional genome of CA1 and CA3 neurons under native conditions and in response to ischemia

Figure 3

Gene ontology analysis for CA3- and CA1-enriched genes in the native state. Bar graph depicting gene ontology (GO) analysis of the genes significantly overexpressed in CA3 or CA1. The upper part of the graph shows the GO category "Biological process", the lower part "Molecular function". GO analysis were performed using the web-based L2L tool [29]. For "Biological process" there is a strong emphasis on terms related to neuron differentiation, synaptic function, and energy metabolism in CA3, and to GABA-signaling in CA1. For "Molecular function" we find enrichment of groups like ephrin receptors, serin-type protease inhibitors, and carbohydrate moiety transfer activities. In contrast in CA1 we observe an enrichment in deglycosylating activity, ligand-gated ion channels, and sulfotransferase activity. Black, expected matches; red, observed matches.

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