Table 4 Genes with down-regulated expression in the heart during iron overload
From: Effects of iron loading on muscle: genome-wide mRNA expression profiling in the mouse
Gene name | Symbol | Accession. | Fold change |
|---|---|---|---|
uncoupling protein 1, mitochondrial | Ucp1 | NM_009463 | -4.47 ** |
actin, alpha 1, skeletal muscle | Acta1 | NM_009606 | -2.79 * |
chemokine (C-X-C motif) ligand 7 | Cxcl7 | NM_023785 | -2.41 * |
stearoyl-Coenzyme A desaturase 1 | Scd1 | NM_009127 | -2.40 ** |
heat shock protein 1B | Hspa1b | NM_010478 | -2.25 ** |
heat shock protein 105 | Hsp105 | NM_013559 | -2.25 ** |
tubulin, beta 1, 2810484G07Rik | Tubb1 | -2.15 * | |
Adipsin | Adn | NM_013459 | -1.92 ** |
carbonic anhydrase 3 | Car3 | NM_007606 | -1.91 ** |
DnaJ (Hsp40) homolog, subfamily B, member 1 | Dnajb1 | NM_018808 | -1.90 ** |
ERBB receptor feedback inhibitor 1 | Errfi1 | NM_133753 | -1.81 ** |
RIKEN full-length enriched library, clone:F830002E14 product: hypothetical Phenylalanine-rich region profile containing protein | AK089567 | -1.69 ** | |
fatty acid synthase | Fasn | NM_007988 | -1.65 ** |
dickkopf homolog 3 (Xenopus laevis) | Dkk3 | NM_015814 | -1.61 * |
Wnt inhibitory factor 1 | Wif1 | NM_011915 | -1.60 ** |
glycoprotein 5 (platelet) | Gp5 | NM_008148 | -1.57 * |
heat shock protein 1, alpha | Hspca | NM_010480 | -1.53 ** |
mt-Nd5 | -1.52 * | ||
adipocyte, C1Q and collagen domain containing | Acdc | NM_009605 | -1.50 ** |
3-hydroxybutyrate dehydrogenase (heart, mitochondrial) | Bdh | NM_175177 | -1.50 * |
heat shock protein 1, beta | Hspcb | NM_008302 | -1.49 ** |
4-aminobutyrate aminotransferase | Abat | NM_172961 | -1.49 ** |
DNA-damage-inducible transcript 4 | Ddit4 | NM_029083 | -1.49 ** |
cyclin-dependent kinase inhibitor 1A | Cdkn1a | NM_007669 | -1.49 ** |
heat shock protein 1 | Hspb1 | NM_013560 | -1.48 ** |
potassium voltage-gated channel, shaker-related subfamily, member 5 | Kcna5 | NM_145983 | -1.46 ** |
CD9 antigen | Cd9 | NM_007657 | -1.45 * |
protein phosphatase 1, regulatory (inhibitor) subunit 3C | Ppp1r3c | NM_016854 | -1.44 ** |
RIKEN full-length enriched library, clone:2510042H12 product: weakly similar to RAT HEMOGLOBIN ALPHA CHAIN (FRAGMENT) [Rattus norvegicus] | AK011092 | -1.44 * | |
immunoglobulin superfamily, member 1 | Igsf1 | NM_183336 | -1.43 ** |
SRY-box containing gene 18 | Sox18 | NM_009236 | -1.42 * |
phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A | Pib5pa | NM_172439 | -1.41 * |
transferrin receptor | Tfrc | NM_011638 | -1.41 ** |
cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 | Chordc1 | NM_025844 | -1.40 ** |
eukaryotic translation elongation factor 2 | Eef2 | NM_007907 | -1.40 ** |
FERM domain containing 5 | Frmd5 | NM_172673 | -1.40 ** |
inhibitor of DNA binding 1 | Idb1 | NM_010495 | -1.40 ** |
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide | P4ha1 | NM_011030 | -1.40 ** |
protein O-fucosyltransferase 2 | Pofut2 | NM_030262 | -1.40 * |
1500015O10Rik | NM_024283 | -1.40 ** |