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Table 2 Biological process GO categories with the lowest mean BMD in zebrafish exposed to EE2

From: BMDExpress: a software tool for the benchmark dose analyses of genomic data

Biological Process GO Categorya Total Genes in Category Genes with BMD Mean BMD (ng/L) Std Dev BMD Mean BMDL (ng/L) Minimum BMD (ng/L) Upregulated/Downregulated Probes
24 h
Protein amino acid glycosylation 24 4 10.88 1.80 7.56 9.47 4/0
Cell migration involved in gastrulation 28 3 12.07 0.82 8.24 11.46 0/3
Monocarboxylic acid metabolic process 28 3 12.30 5.79 8.15 7.90 5/0
tRNA aminoacylation 25 13 12.56 6.62 8.78 5.74 18/0
Nitrogen compound catabolic process 11 3 12.57 1.11 8.53 11.75 0/3
Regulation of apoptosis 45 3 12.76 2.59 8.59 11.24 2/1
Amino acid and derivative metabolic process 83 27 12.94 4.82 8.82 5.74 22/12
Amino acid metabolic process 72 26 12.99 4.91 8.85 5.74 22/11
Amino acid biosynthetic process 18 5 13.05 3.54 8.70 7.90 4/2
Amine metabolic process 99 30 13.07 4.63 8.88 5.74 24/14
168 h
Lipid transport 10 3 11.57 2.54 8.60 8.64 1/3
Response to external stimulus 41 3 15.99 7.96 8.12 10.75 0/3
Glycolysis 33 6 19.75 10.52 13.14 9.27 2/5
Carbohydrate catabolic process 44 7 20.71 9.93 17.79 9.27 3/5
Alcohol metabolic process 61 10 21.39 12.25 13.14 9.27 3/8
Cellular macromolecule catabolic process 79 8 23.02 11.28 18.80 9.27 4/5
Protein-DNA complex assembly 30 3 23.15 16.13 9.61 12.85 1/2
Monosaccharide metabolic process 48 7 23.22 13.28 17.79 9.27 3/5
Cellular protein complex assembly 9 3 23.87 15.67 11.39 10.66 1/2
Protein import 17 3 23.87 15.67 11.39 10.66 1/2
  1. aRedundant child GO categories containing the same genes and mean BMD were removed from the list.