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Figure 5 | BMC Genomics

Figure 5

From: Investigation of factors affecting prediction of protein-protein interaction networks by phylogenetic profiling

Figure 5

Comparison of our result to previous works using Co-Conservation of chemotaxis and flagellar proteins and GGDEF/EAL domains. a) Our refined method. The reference genome is All and Inverse homology applied to Pearson correlation coefficient used as scoring scheme. The confidence of r > 0.8 and threshold E-value 10-5 was used. b) Predicted cluster for flagellar and GGDEF and EAL domains clusters by String (confidence 0.4) c) Predicted cluster for flagellar and GGDEF and EAL domains by Prolinks (confidence 0.6). d) The PPV for the top 2600 predicted pairs by Prolinks versus our method. Our method was Inverse homology applied to Pearson correlation coefficient r > 0.8 with E-value threshold 10-5.

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