Association of the Matrix Attachment Region Recognition Signature with coding regions in Caenorhabditis elegans

BMC Genomics

Table 1 Number of MRS in genic and non-genic portions of the genome.

	genes	exons	introns	5' UTR	3' UTR	intergenic
Size of feature (bp)	58734823	25497325	30586607	456649	1616413	41740777
Number of features in genome	18719	124049	100853	8293	9103	18832
Feature AT%	63	57	68	60	68	66
Actual number of MRS in feature	11368	1955	7094	139	691	12683
Expected number of MRS in feature	14303	4218	5883	33	246	10070
Ratio (actual/expected)	0.79	0.46	1.21	4.22	2.81	1.26
AT% corrected ratio (score system 1)	1.05	1.66	0.74	8.80	1.71	1.02
AT% corrected ratio (score system 2)	1.09	1.83	0.64	2.08	1.34	1.03
AT% corrected ratio (score system 3)	1.07	1.77	0.68	2.98	1.46	1.02
AT correction factor	0.76	0.28	1.64	0.48	1.64	1.24

The number of MRS overlapping genes, exons, introns, 3' UTR, 5' UTR and intergenic regions of the genome was used to calculate an overlap score as described in Methods. The expected overlap score was calculated assuming a uniform distribution of MRS across the genome, using the formulae described in Methods. The ratio of the actual to expected score is shown. This ratio was multiplied by the AT correction factor (see Methods) to give the AT corrected ratio. Score system 1 was used except where indicated otherwise.

ISSN: 1471-2164