Genome-wide changes in expression profile of murine endogenous retroviruses (MuERVs) in distant organs after burn injury

Lee, Young-Kwan; Chew, Alex; Fitzsimon, Lauren; Thomas, Rita; Greenhalgh, David; Cho, Kiho

doi:10.1186/1471-2164-8-440

Table 1 Summary of tropism characteristics of 31 unique MuERV U3 sequences

From: Genome-wide changes in expression profile of murine endogenous retroviruses (MuERVs) in distant organs after burn injury

Group	U3	Direct repeat/Unique region					Tropism
		1/1*	2	4/4*	5/5*	6/6*
	U-4-7 U3	Poly	X-I, II, IV, Poly	Poly	Poly	X-I, Poly	P-II
	U-4-8 U3	Poly	X-III, Poly	Poly	Poly	X-I, II, III, IV, Poly	P-I
	U-2-7 U3	Poly	X-III, Poly	Poly	Poly	X-I, II, III, IV, Poly	P-I
	K-4-11 U3	Poly	X-III, Poly	Poly	Poly	X-I, II, III, IV, Poly	P-I
	K-4-8 U3	•	X-I, II, IV, Poly	X-II	X-II, III, IV	X-I, II, III, IV, Poly	X-II
Isolated in Burn	U-4-9 U3	•	X-I, II, IV, Poly	X-I	X-II, IIII, IV	X-I, Poly	X-I
	U-4-11 U3	•	X-I, II, IV, Poly	X-I	X-II, III, IV	X-I, II, III	X-I
	U-4-1 U3	•	X-I, II, IV, Poly	X-III	•	X-I, II, III, IV, Poly	X-III
	K-4-10 U3	•	X-I, II, IV, Poly	X-III	•	X-I, II, III, IV, Poly	X-III
	K-4-5 U3	•	X-I, II, IV, Poly	X-III	•	X-I, II, III, IV, Poly	X-III
	L-4-3 U3	•	X-I, II, IV, Poly	X-III	•	X-I, II, III, IV, Poly	X-III
	U-3-4 U3	Poly	X-III, Poly	Poly	Poly	X-I, II, III, IV, Poly	P-II
Burn/No Burn	L-3-2 U3	X-III	X-I, II, IV, Poly	X-II	X-II, III, IV	X-I, II, III, IV, Poly	X-II
	L-1-1 U3	•	X-I, II, IV, Poly	X-III	•	X-I, II, III, IV, Poly	X-III
	U-1-7 U3	X-II, III	X-I, II, IV, Poly	Poly	Poly	X-I, Poly	P-II
	K-3-3 U3	X-II, III	X-I, II, IV, Poly	Poly	Poly	X-I, Poly	P-II
	K-3-6 U3	X-II, III	X-I, II, IV, Poly	Poly	Poly	X-I, Poly	P-II
	K-3-8 U3	X-II, III	X-I, II, IV, Poly	Poly	Poly	X-I, Poly	P-II
	L-3-5 U3	X-II, III	X-II, III	Poly	Poly	X-I, Poly	P-II
	L-3-1 U3	Poly	X-III, Poly	Poly	Poly	X-I, II, III, IV, Poly	P-I
	L-3-4 U3	Poly	X-III, Poly	Poly	Poly	X-I, II, III, IV, Poly	P-I
Isolated in No Burn	U-1-5 U3	Poly	X-III, Poly	Poly	Poly	X-I, II, III, IV, Poly	P-I
	U-3-2 U3	Poly	X-III, Poly	Poly	Poly	X-I, II, III, IV, Poly	P-I
	L-1-2 U3	X-II, III	X-III, Poly	Poly	X-II, III, IV	X-I, II, III	X-III
	U-1-1 U3	X-II, III	X-III, Poly	X-III	X-II, III, IV	X-I, II, III	X-III
	L-1-6 U3	X-III	X-I, II, IV, Poly	X-III	X-II, III, IV	X-I, II, III, IV, Poly	X-III
	L-1-8 U3	X-III	X-I, II, IV, Poly	X-II	X-II, III, IV	X-I, II, III, IV, Poly	X-II
	K-3-5 U3	X-II, III	X-I, II, IV, Poly	X-II	X-II, III, IV	X-I, II, III	X-II
	L-3-9 U3	•	X-I, II, IV, Poly	X-I	X-II, III, IV	X-I, Poly	X-I
	U-3-8 U3	•	X-I, II, IV, Poly	X-I	X-II, III, IV	X-I, Poly	X-I
	U-1-8 U3	•	X-I, II, IV, Poly	X-III	•	X-I, II, III, IV, Poly	X-III

Dot indicates absence of a homology with reference sequences. Underline represents the reference type closest to individual U3 sequences examined. Naming scheme of U3 sequence: Letter (K-kidney; L-liver; U-lung), first number ("1"–3 hours control; "2"–3 hours burn; "3"–24 hours control; "4"–24 hours burn), and second number (clone number). *Direct repeat region.

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ISSN: 1471-2164

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