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Table 1 NeuroStem chip entries related to dopaminergic system.

From: "NeuroStem Chip": a novel highly specialized tool to study neural differentiation pathways in human stem cells

Genesa

Function

Aadc, Ant2 (Slc25a5), Calb1, Dat (Slc6a3), Girk2 (Kcnj6), Igf1, Ptx3, Th

Markers of dopaminergic neurons

En1, En2, Lmx1bb, Pax5, Shh, Wnt1

Markers of dopaminergic progenitors

Adh2, Lhx1 (Lim1), Lhx5 (Lim2)

Markers of dopaminergic progenitors maturation

Drd2b, Vmat2

Markers of mature dopaminergic neurons

Gfra1, Gfra2, Gfra3, Gfra4, Otx2

Markers of early dopaminergic neurons

Dlx1, Dlx2, Flj38973, Lmx1a

Related to differentiation of dopaminergic neurons

Adcy7, Alcam, Art (Artn), Bcl11a, Calca, Cart, Cbln1, Cdh2, Col11a1, Cx43, D1lip (Drd1ip), Darpp32 (Ppp1r1b), Dbh, Doc2a, Drd1, Drd3, Drd4, Drd5, Drip78 (Dnajc14), Egln3 (Phd3), Egr1, Fos, Fxyd6, Galm, Ghr, Grin2c, Grp, Gsbs (C7orf16), Hs6st2, Igfbp4, Kcna5, Kcnab1, Math2, Mlp (Marcksl1), Moxd1, Mpp3, Nrip3, Nrp2, Nt (Nts), Ntn (Nrtn), Nurr1 (Nr4a2), Pac1 (Adcyap1r1), Pacap, Plagl1 (Zac), Pvrl3 (Nectin 3), Rab3c, Rcn1, Slc17a6 (Vglut2), Slc6a1, Sox6, Spp1, Tacr3, Trhr, Zfp161, Vav3, Zdhhc2

Related to dopaminergic system

  1. The majority of genes listed may also possess other functions, not related to dopaminergic system. Four entries were omitted from the table, representing candidate markers of dopaminergic system now undergoing characterization (unpublished data).
  2. a Italics indicates genes up-regulated (Log2 ratio >1.0) in dopaminergic differentiation experiment. Rcn1, Log2 ratio >0.97; Fxyd6 and Zfp161, Log2 ratio >0.7).
  3. b May also possess other functions related to dopaminergic system.