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Table 3 Functional classification of predicted proteins

From: The fungus Ustilago maydis and humans share disease-related proteins that are not found in Saccharomyces cerevisiae

  Protein number P-value
A. U. maydis – S. cerevisiae *   
   1. Biosynthesis* 75 1,7e-33
   2. Spore formation/budding/cell polarity 68 1.9e-15
   3. Transport** 49 1.3e-18
   4. Ion homeostasis 36 4.2e-12
   5. Stress response$ 35 7.5e-11
   6. Detoxification/Resistance 29 1.4e-10
   7. Unknown function 96 1
B. U. maydis – H. sapiens *   
   1. mRNA splicing 38 6.9e-17
   2. Protein modification/degradation 29 2.4e-04
   3. G-protein-mediated signalling 17 3,6e-06
   4. Amino acid degradation 14 4.4e-09
   5. Oxidation of fatty acids 10 1.1e-05
   6. Unknown function 222 1
C. S. cerevisiae – H. sapiens *   
   1. Biosynthesis, secondary§ 105 3.0e-05
   2. Protein fate, – modification 89 7.4e-06
   3. Oxidative stress response 8 3.7e-03
   4. tRNA modification 7 3.4e-03
   5. Unknown function 46 1
  1. *Note that proteins can appear in more than one functional category. In addition, numerous proteins are assigned to additional functional classes that are not listed.
  2. Only those predicted proteins were considered that (1) show more than 20% identity with either in both organisms and (2) show at least 10 % less homology in the third partner
  3. *Amino acids/vitamins/cofactors
  4. **Amino acids/lipids/carbohydrates
  5. $Salt and oxidative stress
  6. §Polyamines, vitamins, co-factors and other secondary products
  7. Predicted proteins are not found in the COGs or FunCat database