Table 3 Iron regulated genes that are common between A. pleuropneumoniae (App) and P. multocida (Pm)
From: Transcriptional profiling of Actinobacillus pleuropneumoniae under iron-restricted conditions
App Gene ID | Gene | Pm ORF | Description |
|---|---|---|---|
Up-Regulated genes | |||
ap1453 | omp64 | 576 | CopB homolog, heme-hemopexin utilization protein C |
ap2032 | lldD | 288 | l-lactate dehydrogenase |
ap0294 | yfeB | 399 | chelated iron transport, ATP binding protein |
ap0295-ap0296 | yfeA | 400 | chelated iron transport, periplasmic binding protein |
ap1739 | exbB | 1186 | energy transducing protein |
ap0145 | yfeC | 398 | chelated iron transport, membrane protein |
ap0726 | hlyX | 668 | fnr-like transcriptional regulator |
ap0144 | yfeD | 129 | chelated iron transport, membrane protein |
ap1175-ap1176 | hgbA | 741 | hemoglobin-bindin protein precursor |
ap1740 ap0082 | tonB1 tonB2 | 1188 | energy transducing protein |
ap0755 | aroA | 839 | conserved hypothetical protein |
ap1738 | exbD | 1187 | biopolymer transport protein |
ap0286 | nagB | 875 | conserved hypothetical protein |
ap1505 | HI1275 | 656 | tellurite resistance protein TehB |
ap1363 | fldA | 353 | flavodoxin |
Down-Regulated genes | |||
ap0108 | nrfA | 1792 | nitrate reductase cytochrome c552 |
ap1470 ap1698 | dcuB1 dcuB2 | 1434 | anaerobic C4-dicarboxylate membrane transporter |
ap0169-ap0173 | aopA, nqrBCDE | 1331 | NADH: ubiquinone oxydoreductase |
ap1937 | fumC | 823 | fumarate hydratase class II |
ap1588 | napF | 1592 | ferredoxin-type protein |
ap1822 | atpH | 1491 | ATP synthase delta subunit |
ap0996-ap0997 | bisC | 408-409 | nitrate-inducible formate dehydrogenase-N α subunit |
ap0725 | uspA | 1286 | universal stress protein A |
ap1478 | ptsI | 897 | phosphoenolpyruvate PTS system enzyme I |
ap1477 | ptsH | 898 | phosphocarrier protein Hpr |
ap1163 | pflB | 75 | formate acetyltransferase |
ap0684 | bioD1 | 641 | probable dethiobiotin synthetase |
ap1402 | pgk | 1860 | phosphoglycerate kinase |
ap1848 | dmsA | 1754 | dimethyl sulfoxide reductase |
ap0998 | hybA | 407 | formate dehydrogenase β subunit |
ap0484 | gapA | 924 | glyceraldehyde 3-phosphate dehydrogenase |
ap1694-ap1692 | frdABC | 201-199 | fumarate reductase |
ap1132 | adh2 | 1453 | alcohol dehydrogenase 2 |
ap1215 | ompW | 331 | outer membrane protein W |