Factor | Diagnostic signature n = 177 | Prognostic signature n = 89 |
---|---|---|
Sex (male/female) | 88/89 | 50/39 |
Age, median (range) years | 66 (11 – 94) | 69 (33 – 93) |
Histological subtypes | Â | Â |
   Malignant fibrous histiocytoma (MFH) | 61¤ | 54 |
   Leiomyosarcoma | 40 | 27 |
   Synovial sarcoma | 32 | 0 |
   Liposarcoma | 16* | 0 |
   Malignant peripheral nerve sheath tumor | 8 | 0 |
   Myofibroblastic sarcoma | 5 | 5 |
   STS not otherwise specified | 4 | 2 |
   Extraskeletal osteosarcoma | 3 | 1 |
   Fibrosarcoma | 3 | 0 |
   Gastrointestinal stromal tumors | 3 | 0 |
   Epithelioid sarcoma | 1 | 0 |
   Malignant mesenchymoma | 1 | 0 |
Grade | Â | Â |
   II | 6 | 1 |
   III | 32 | 12 |
   IV | 139 | 76 |
Tumor size | Â | Â |
   Median (range) cm | 8 (1–40) | 9 (2–30) |
   < 5 cm | 41 | 19 |
   5 – 10 cm | 74 | 38 |
   >10 cm | 62 | 32 |
Tumor location | Â | Â |
   Extremity | 144 | 78 |
   Trunk wall | 19 | 7 |
   Retroperitoneum | 7 | 3 |
   Other | 7# | 1 |
Tumor depth | Â | Â |
   Superficial | 37 | 22 |
   Deep | 118 | 63 |
   Unclassified | 22 | 4 |
Necrosis | Â | Â |
   Absent | 48 | 23 |
   Present | 106 | 66 |
   Unclassified | 23 | 0 |
Vascular invasion | Â | Â |
   Absent | 121 | 72 |
   Present | 31 | 17 |
   Unclassified | 25 | 0 |
Treatment | Â | Â |
   Surgery alone | 107 | 58 |
   Postoperative radiotherapy | 51 | 22 |
   Postoperative chemotherapy | 3 | 2 |
   Postoperative radio- and chemotherapy | 10 | 7 |
   Preoperative radio- or chemotherapy | 6 | 0 |
Surgery | Â | Â |
   Wide | 90 | 57 |
   Marginal | 66 | 28 |
   Intralesional | 15 | 4 |
   Unclassified | 6 | 0 |