Table 1 Genes listed in the tryptophan pathway in KEGG.

AADAT

aminoadipate aminotransferase

HEMK1

HemK methyltransferase family member 1

AANAT

Arylalkylamine N-acetyltransferase

HSD17B10, HADH2

hydroxysteroid (17-beta-dehydrogenase)

ABP1

Amiloride binding protein 1

HSD17B4

hydroxysteroid

ACAT1, ACAT

acetyl-Coenzyme A acetyltransferase 1

INDO, IDO

indoleamine-pyrrole 2,3 dioxygenase

ACAT2

acetyl-Coenzyme A acetyltransferase 2

INDOL1

indoleamine-pyrrole 2,3 dioxygenase-like 1

ACMSD

Aminocarboxymuconate semialdehyde decarboxylase

INMT

indolethylamine N-methyltransferase

AFMID

Arylformamidase

KMO

Kynurenine 3-monooxygenase

ALDH1A3

Aldehyde dehydrogenase 1 family, member A

KYNU

kynureninase

ALDH1B1

Aldehyde dehydrogenase 1 family, member B

LCMT1

Leucine carboxyl methyltransferase 1

ALDH2

Aldehyde dehydrogenase 2 family

LCMT2

Leucine carboxyl methyltransferase 2

ALDH3A1, ALDH3

Aldehyde dehydrogenase 3 family

LNX1

ligand of numb-protein X 1

ALDH3A2

Aldehyde dehydrogenase 3 family, member A

MAOA

monoamine oxidase A

ALDH7A1

Aldehyde dehydrogenase 7 family, member A

MAOB

monoamine oxidase B

ALDH9A1

Aldehyde dehydrogenase 9 family, member A

METTL2B, METTL2

methyltransferase like 2B

AOC2

amine oxidase, copper containing 2

METTL6

methyltransferase like 6

AOC3

amine oxidase, copper containing 3

NFX1

nuclear transcription factor, X-box binding

AOX1

Aldehyde oxidase 1

OGDH

oxoglutarate

ASMT

acetylserotonin O-methyltransferase

OGDHL

oxoglutarate dehydrogenase-like

CARM1

Coactivator-associated arginine methyltransferase

PRMT2, HRMT1L1

Protein arginine methyltransferase

CAT

Catalase

PRMT3, HRMT1L3

Protein arginine methyltransferase

CYP1A1, CYP1

Cytochrome P450, family 1, subfamily A

PRMT5

Protein arginine methyltransferase 5

CYP1A2

Cytochrome P450, family 1, subfamily A

PRMT6, HRMT1L6

Protein arginine methyltransferase

CYP1B1, GLC3A

cytochrome P450, family 1, subfamily B

PRMT7

Protein arginine methyltransferase 7

DDC

dopa decarboxylase

PRMT8, HRMT1L3, HRMT1L4

Protein arginine methyltransferase

ECHS1

enoyl Coenzyme A hydratase, short chain, 1,

TDO2

Tryptophan 2,3-dioxygenase

EHHADH

enoyl-Coenzyme A

TPH1, TPRH, TPH

Tryptophan hydroxylase 1

GCDH

glutaryl-Coenzyme A dehydrogenase

TPH2

Tryptophan hydroxylase 2

HAAO

3-hydroxyanthranilate 3,4-dioxygenase

WARS, IFI53

tryptophanyl-tRNA synthetase

HADH, HADHSC

hydroxyacyl-Coenzyme A dehydrogenase

WARS2

tryptophanyl tRNA synthetase 2, mitochondrial

HADHA

hydroxyacyl-Coenzyme A dehydrogenase

WBSCR22

Williams Beuren syndrome chromosome region