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Table 5 Summary of GO categories that show significant conservation tendencies for both protein and promoter sequences.

From: Weak correlation between sequence conservation in promoter regions and in protein-coding regions of human-mouse orthologous gene pairs

Promoter conservation    
  High F:receptor binding (221) * P:regulation of transcription (602) *
   P:cell-cell signaling (176) * F:transcription factor activity (263) *
   C:extracellular matrix (111) * P:transcription (640) *
   P:cell adhesion (242) P:nervous system development (154) *
   C:plasma membrane (608) F:cytoskeletal protein binding (137) *
    F:ion channel activity (98) *
    C:actin cytoskeleton (85) *
    P:protein amino acid phosphorylation (213) *
    F:protein kinase activity (220) *
    P:intracellular signaling cascade (431) *
  Low P:proteolysis (259) * P:protein biosynthesis (283) *
   F:peptidase activity (227) * F:structural constituent of ribosome (130) *
   P:immune response (270) C:ribosome (114) *
   P:response to biotic stimulus (318)  
   F:nuclease activity (60) *  
   C:peroxisome (49) *  
   P:electron transport (151) *  
   P:carboxylic acid metabolism (225)  
   P:lipid metabolism (260) *  
   C:lysosome (77) *  
   F:oxidoreductase activity (309) *  
   C:mitochondrion (398) *  
   Low High
   Protein conservation
  1. In each cell, the GO categories are ordered by promoter conservation. The number of genes for each term is shown in parentheses. GO annotations associated with human genes were used to make this table. '*' represent GO terms that show a significant tendency not only for the human annotation but also for the mouse annotation.