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Table 1 Potential inconsistencies for gene regulatory interactions given a gene expression study.

From: Linking Cytoscape and the corynebacterial reference database CoryneRegNet

TF expr. t

Target gene expr. g

Regulation type r

Contradiction?

+

+

-

yes

+

-

+

yes

-

+

+

yes

-

-

-

yes

+

+

+

no

+

-

-

no

-

+

-

no

-

-

+

no

  1. This table illustrates all gene expression/regulation combinations for a transcription factor T (with relative expression level t), a target gene G (with relative expression level g), and a regulatory interaction of type r. For the first four rows, COMA would suggest that the gene regulation type r contradicts the given gene expression levels for the transcription factor T and the target gene G.