Skip to main content

Table 3 Genes with significantly altered expression in the STG in schizophrenia according to functional group.

From: Altered gene expression in the superior temporal gyrus in schizophrenia

Functional Group GenBank ID Name Symbol Cytoband # pairs changed/7 Average Fold Change
Neuro- transmission NM_000834 Glutamate receptor, ionotropic, N-methyl D-aspartate 2B GRIN2B 12p12 4 1.98
  AL157442 Glutamate receptor, ionotropic, N-methyl D-asparate-associated protein 1 (glutamate binding) GRINA 8q24.3 6 -2.33
  AK024507 Glutamate receptor interacting protein 2 GRIP2 3p24-p23 4 -1.73
  AB043997 Solute carrier family 5 (choline transporter), member 7 SLC5A7 2q12 5 2.07
  AF263613 Intracellular membrane-associated calcium-independent phospholipase A2 gamma* IPLA2(γ) 7q31 6 1.88
  AF311862 Lin-7 homolog B (C. elegans) LIN7B 19q13.3 6 -3.00
  AL137559 Synaptotagmin VII SYT7 11q12-q13.1 4 -1.90
  NM_007232 Histamine receptor H3 HRH3 20q13.33 4 -2.00
Presynaptic function AJ132089 Dynein, axonemal, heavy polypeptide 10 DNAH10 12q24.31 6 4.08
  AB011131 Piccolo* PCLO 7q11.23-q21.3 4 -2.23
Myelination AF179481 Acyl-CoA synthetase bubblegum family member 1* Ascbg1 15q23-q24 5 -1.94
Neuro- development AL050059 Disabled homolog 1 (Drosophila) DAB1 1p32-p31 4 -2.49
  NM_006885 AT-binding transcription factor 1 ATBF1 16q22.3-q23.1 6 2.77
  NM_006156 Neural precursor cell expressed, developmentally down-regulated 8 NEDD8 14q11.2 5 -2.62
  AF087991 Netrin G1 NTNG1 1p13.3 5 -2.57
  AF009311 Semaphorin 5A SEMA5A 5p15.2 4 2.23
Intracellular signalling M61906 Phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) PIK3R1 5q13.1 7 4.10
  NM_003632 Contactin associated protein 1 CNTNAP1 17q21 4 -2.74
  NM_006078 Calcium channel, voltage-dependent, gamma subunit 2 CACNG2 22q13.1 4 -2.16
  NM_003385 Visinin-like 1 VSNL1 2p24.3 5 -2.15
  NM_005031 FXYD domain containing ion transport regulator 1 (phospholemman)* FXYD1 19q13.1 5 -3.07
Other brain related illnesses NM_005503 Amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like) APBA2 15q11-q12 4 -2.55
  NM_004860 Fragile × mental retardation, autosomal homolog 2 FXR2 17p13.1 5 -2.16
Other functions AB002340 Lupus brain antigen 1 LBA1 3p22.3 4 -1.89
  NM_002629 Phosphoglycerate mutase 1 (brain) PGAM1 10q25.3 4 -2.18
  NM_016223 Protein kinase C and casein kinase substrate in neurons 3 PACSIN3 11p12-p11.12 5 -2.22
  NM_005619 Reticulon 2 RTN2 19q13.32 4 -1.72
  NM_001048 Somatostatin SST 3q28 5 -3.02
  U27768 Regulator of G-protein signalling 4* RGS4 1q23.3 4 -1.79
  M96577 E2F transcription factor 1 E2F1 20q11.2 6 -2.59
  AK023573 Synapse defective 1, Rho GTPase, homolog 1 (C. elegans) 7h3 19p13.12 4 -1.71
  X87825 Olfactory receptor, family 7, subfamily E, member 47 pseudogene OR7E47P 12q13.13 6 7.32
  X89668 Olfactory receptor, family 7, subfamily E, member 19 pseudogene OR7E19P 19p13.2 7 2.23
  1. *Previously reported to be altered in schizophrenia.