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Figure 5 | BMC Genomics

Figure 5

From: Evolutionary rates and patterns for human transcription factor binding sites derived from repetitive DNA

Figure 5

Site-specific variation scores for TE-derived versus non-repetitive TFBS. (A & C) Frequency distributions of scores for 1,000 simulated genome-random sequences (pink), repeat-random sequences (green) and matrix-random sequences (blue) for the M00671 matrix representing the TFBS bound by TCF-4 (A) and the M01037 matrix for TFBS bound by GLI1 (C). (B & D) The matrix-random score distributions are compared to the scores for individual TFBS derived from TEs (red) versus the non-repetitive TEs (gray). Data are shown for M00671 TCF-4 (B) and M01037 GLI1 (D).

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